Polish

Department of Microbiology and Clinical Immunology

Research

Research

Scientific and research activities:

The department conducts research in four main directions:

  1. Improvement of diagnostic methods for viral and bacterial diseases in animals using immunological methods and molecular biology,
  2. Application of immunomodulation in animal health protection,
  3. Effects of xenobiotics on immunocompetent cells and non-specific defense mechanisms and anti-infective immunity of animals,
  4. Improvement of methods of prevention and therapy of infectious diseases in fish, birds and mammals.

            In the field of diagnostic research, the sensitivity of immunological and biological methods (fixed cell lines, embryos) and PCR techniques in identifying viruses pathogenic to animals is being evaluated. At the same time, cutting-edge research is being conducted on stimulating non-specific cellular and humoral defense mechanisms and specific immune responses to vaccine antigens using synthetic and natural immunomodulators. In the field of immunotoxicology research, in vitro and in vivo techniques are being perfected to determine the effects of xenobiotics on the activity of phagocytic cells (PMN and MN) and T and B lymphocytes. Studies are being performed on the effects of xenobiotics on the number and activity of antibody-producing cells (ASCs) and the specific immune response. Equally innovative is research on shielding immunohomeostasis through the use of biopreparations. The department also conducts systematic research on the sensitivity of bacteria to selected groups of chemotherapeutics, with the determination of effective doses for different animal species