Lecture No 1: General toxicology and basic information about poisons and harmful substances. Poison, poisoning, xenobiotic, persistent substance. Category of poisons. Types of poisoning. Dose of poison, time of exposure to the poison, and its effect.
Lecture No 2: The mechanism of action of poisons on the body and the factors that determine the toxic effect of the poison, the occurrence and course of poisoning. Modes of action of poisons on the animal body at the systemic, tissue, cellular, subcellular and molecular levels. Factors on which the toxic properties of a poison depend. Factors that determine the occurrence and course of poisoning.
Lecture No 3 and 4: The fate of poisons in the body. Pathways of absorption of poisons. Distribution and their accumulation. Biotransformation of xenobiotics (hydrolysis, reduction, oxidation and conjugation processes). Routes of excreting poisons from the body. General diagnosis of poisonings and principles of prevention and treatment of poisonings.
Lecture No 5: Poisoning with corrosive substances (mechanism of action, clinical symptoms, anatomopathological lesions, treatment and prevention of poisoning). Acids, alkalis, batteries, cationic detergents.
Lecture No 6 and 7: Metal poisoning of animals (circumstances of poisoning, mechanism of action, clinical symptoms, anatomopathological lesions, treatment and prevention of poisoning). Chromium, zinc, aluminum, cobalt, manganese, molybdenum, iroron.
Lecture No 8: Poisoning of animals with non-metals (circumstances of poisoning, mechanism of action, clinical symptoms, anatomopathological lesion, treatment and prevention of poisoning). Phosphorus and its compounds, selenium and its compounds, halogens (fluorine, chlorine, bromine, iodine).
Lecture No 9: Poisoning with organic compounds (circumstances of poisoning, mechanism of action, clinical symptoms in animals, anatomopathological lesions, prognosis, treatment and prevention of poisoning). Benzene, toluene, xylene, dioxins.
Lecture No 10-12: Pesticide poisoning (classification, mechanism of action, clinical symptoms, anatomopathological lesions, prognosis, treatment and prevention of poisoning). Insecticides. Herbicides, fungicides, snailicides.
Lecture No 13-15: Poisoning with plants and mushrooms (list of poisonous plants and mushrooms, compounds found in plants and mushrooms, circumstances of poisoning, clinical symptoms and anatomopathological lesions, prognosis, treatment and prevention of poisoning).
Classes No 1: General Toxicology I
Classes No 2: Describing samples intended for toxicological testing. Arsenic and mercury determination methods
Classes No 3: Quick assays in mineral identification: lead (Pb), mercury (Hg), copper (Cu), arsenic (As)
Classes No 4: Qualitative nitrate/nitrite determination in biological samples
Classes No 5: Chlorine, nitrogen, phenol and detergents determination in biological samples
Classes No 6: Toxicity of glycosides, plant alkaloids and selcted drugs. Biological tests in veterinary toxicology. Selected methods to determine LD50 – Kärber’s method for measuring of acute toxicity.
Classes No 7: Colloquium no 1
Classes No 8: Colorimetric determination of red blood cell acetylcholiesterase activity
Classes No 9: Toxicity of organophosphate insecticides
Classes No 10: Toxicity of rodenticides (anticoagulant rodenticides and cholecalciferol (vit. D)
Classes No 11: Toxicity of herbicydes (derivatives of 2,4-Dichlorophenoxyacetic acid) and fungicides (ditiocarbamid acid derivates)
Classes No 12: Feed poisoning of farm animals. Toxicity of urea for animals.
Classes No 13: Colloquium no 2
Classes No 14: Air pollution by NO, CO, H2S, SO2, NH3, NO2
Classes No 15: Toxicity of N-nitrosamines
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